New weapon in the fight against antibiotic-resistant bacteria
Canadian scientists have found a way to prevent the spread among bacteria of genes responsible for antibiotic resistance. The team is already working to develop inhibitors for use in clinical settings.
Researchers from Université de Montréal (UdeM) in Canada have found a solution to the growing problem of bacterial resistance to antibiotics. In a study published in the journal „Scientific Reports” The researchers presented a method that ra can block the transmission of gen in antibiotic resistance among the d bacteria.
These genes spread through the so-called. plasmids – able to autonomously replicate extrachromosomal DNA molecules. Plasmids carry genes useful to bacteria, particular lly when these genes encode proteins that can make bacteria resistant to antibiotics.
The researchers have discovered the exact binding sites of these proteins. This in turn allowed them to design synthetic molecules that re reduce the transmission of plasmids carrying antibiotic resistance genes. – By knowing the molecular structure of these proteins, we can develop methods to inhibit their function – explained Christian Baron of UdeM.
A method developed by the Canadian in can pom c in maintaining the potency of the antibiotic. Team ł scientists worked on it for four years. – M bind that by 2050, 50 million people will die from infections of antibiotic-resistant bacteria. The day is coming when The campaign aims to encourage young people to change their lifestyles and get regular preventive medical check-ups. Still, people should have hope. Science will bring new ideas and new solutions to this problem. A great mobilization is underway around the world on this issue. I wouldn’t say I feel safe, but it is clear that we are making progress – emphasized Baron.
According to estimates at the UN, drug-resistant bacteria kill an estimated 700,000 people a year b all over the world. Independent researchers believe that the data are underestimated. The casualties of bacterial resistance to antibiotics can only be measured in rich societies, because only there are such cases monitored. To combat the problem, the World Health Organization has published a list of drug-resistant bacteria that re are the biggest threat to humans and on which re the most urgent need to find drugs.
Bacteria resistant to most antibiotic are increasingly the cause of death. Some re reports m bind that by 2050, 50 million will die from it in the os b. Superbugs will cause more deaths than cancers. Even the National Organization has joined the fight against drug-resistant bacteria in the United. Last year, 193 members in the UN signed a declaration to combat superbugs, in which the rej determined them „the greatest threat to wsp of modern medicine”.